Overview
| Product name | GSK3β Rabbit pAb |
|---|---|
| Catalog No. | A16868 |
| Host species | Rabbit |
| Purification method | Affinity purification |
| Isotype | IgG |
Background
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Immunogen information
| Immunogen | Recombinant protein of human GSK3β. |
|---|---|
| Sequence | Email for sequence |
| Gene ID | 2932 |
| Swiss prot | P49841 |
| Synonyms | GSK3B; gsk-3β |
| Calculated MW | 46kDa/48kDa |
| Observed MW | 47kDa |
Applications
| Reactivity | Human, Mouse, Rat |
|---|---|
| Tested applications | WBIP |
| Recommended dilution | WB 1:500 - 1:2000 IP 1:50 - 1:100 |
| Storage buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Application key | Western blotting Immunoprecipitation |
| Positive samples | HeLa, LO2, mouse thymus, mouse testis, rat brain |
| Cellular location | Cell membrane, Cytoplasm, Nucleus |
